Recherche et enseignement

Recherche clinique : 
 

L’objectif de la recherche clinique est de développer les connaissances scientifiques afin d’améliorer la qualité des prestations de soins, l’état de santé de la population et les performances du système de soins.

Afin d’assurer la qualité des données qu’elles produisent mais avant tout de protéger les personnes qui s’y prêtes, les études sont conduites conformément à la règlementation en vigueur.



 

Les patients répondant aux critères d’éligibilité propres à chaque étude doivent accepter d’y participer de façon expresse et éclairée après avoir été pleinement informés du déroulement, des éventuels bénéfices et risques de l’étude et peuvent s’en retirer à tout moment, sans justification et sans que cela n’ait d’impact sur la suite de leur prise en charge.

Tout doit être mis en œuvre afin d’assurer la sécurité et le respect des droits des patients ainsi que le respect du protocole durant l’étude.

Dans le service, une douzaine d’études nationales ou internationales sont actuellement en cours sur le rachis ou les lésions cérébrales.

Articles universitaires :
 
Everolimus and Octreotide for Patients with Recurrent Meningioma: Results from the Phase II CEVOREM Trial.
Graillon T, Sanson M, Campello C, Idbaih A, Peyre M, Peyrière H, Basset N, Autran D, Roche C, Kalamarides M, Roche PH, Fuentes S, Tabouret E, Barrie M, Cohen A, Honoré S, Boucekine M, Baumstarck K, Figarella-Branger D, Barlier A, Dufour H, Chinot OL.
Clin Cancer Res. 2020 Feb 1;26(3):552-557.
 
Does the hip positioning matter for oblique lumbar interbody fusion approach? A morphometric study.
Farah K, Leroy HA, Karnoub MA, Obled L, Fuentes S, Assaker R.
Eur Spine J. 2020 Feb;29(2):306-313.
 
Optimizing medical postoperative care: Role of the hospitalist in a department of adult neurosurgery. Prospective comparative observational study.
Dufour H, Rousseau-Ventos D.
Neurochirurgie. 2020 Jan 14. 
 
Fluctuation analysis of postoperative secretory status in patients operated for acromegaly.
Graillon T, Castinetti F, Boucekine M, Cuny T, Morange I, Fuentes S, Figarella-Branger D, Albarel F, Brue T, Dufour H.
Ann Endocrinol (Paris). 2019 Dec 19.
 
Minimal invasive percutaneous C1C2 fixation using an intraoperative 3D imaging-based navigation system on management of odontoid fractures.
Meyer M, Farah K, Graillon T, Dufour H, Blondel B, Fuentes S.
World Neurosurg. 2019 Dec 18.
 
Minimally invasive posterior fixation and anterior debridement-fusion for thoracolumbar spondylodiscitis: A 40-case series and review of the literature.
Farah K, Peyriere H, Graillon T, Prost S, Dufour H, Blondel B, Fuentes S.
Neurochirurgie. 2019 Dec 10. 
 
Management of two cavernous sinus dural arteriovenous fistulae by direct microsurgical approach and catheterization of the superior ophthalmic vein.
Serratrice N, Baucher G, Reyre A, Brunel H, Fuentes S, Dufour H.
Neurochirurgie. 2019 Dec;65(6):397-401.
 
Letter to the Editor: "Why We Should Still Treat by Neurosurgery Patients With Cushing Disease and a Normal or Inconclusive Pituitary MRI".
Castinetti F, Graillon T, Dufour H, Brue T.
J Clin Endocrinol Metab. 2019 Dec 1;104(12):5791-5792. 
 
Clinical presentation, treatment and outcome of IgG4-related pachymeningitis: From a national case registry and literature review.
Melenotte C, Seguier J, Ebbo M, Kaphan E, Bernit E, Saillier L, Audoin B, Feyeux D, Daniel L, Roche PH, Graillon T, Dufour H, Boutière C, Girard N, Closs-Prophette F, Guillaud C, Tieulié N, Regent A, Harlé JR, Hamidou M, Mekinian A, Grados A, Schleinitz N.
Semin Arthritis Rheum. 2019 Dec;49(3):430-437.
 
A prospective, international, randomized, noninferiority study comparing an implantable titanium vertebral augmentation device versus balloon kyphoplasty in the reduction of vertebral compression fractures (SAKOS study).
Noriega D, Marcia S, Theumann N, Blondel B, Simon A, Hassel F, Maestretti G, Petit A, Weidle PA, Mandly AG, Kaya JM, Touta A, Fuentes S, Pflugmacher R.
Spine J. 2019 Nov;19(11):1782-1795. 
 
Surgical indications for pituitary tumors during pregnancy: a literature review.
Graillon T, Cuny T, Castinetti F, Courbière B, Cousin M, Albarel F, Morange I, Bruder N, Brue T, Dufour H.
Pituitary. 2019 Nov 6.
 
Computation of Intersegmental Moments during Standing Posture: Can We Neglect the Horizontal Ground Reaction Force? Results from an Experimental Study.
Prost S, Pesenti S, Moal B, Pomero V, Fuentes S, Tropiano P, Lafage V, Jouve JL, Blondel B.
Adv Orthop. 2019 Nov 13;2019:7129682.
 
Interfascial approach for pterional craniotomy: technique and adjustments to prevent cosmetic complications.
Baucher G, Bernard F, Graillon T, Dufour H.
Acta Neurochir (Wien). 2019 Nov;161(11):2353-2357.
 
Acromegaly in Carney complex.
Cuny T, Mac TT, Romanet P, Dufour H, Morange I, Albarel F, Lagarde A, Castinetti F, Graillon T, North MO, Barlier A, Brue T.
Pituitary. 2019 Oct;22(5):456-466. 
 
In Reply: Predictive Factors of Surgical Outcome in Frontal Lobe Epilepsy Explored with Stereoelectroencephalography.
Bonini F, McGonigal A, Scavarda D, Carron R, Régis J, Dufour H, Péragut JC, Laguitton V, Villeneuve N, Chauvel P, Giusiano B, Trebuchon A, Bartolomei F.
Neurosurgery. 2019 Oct 1;85(4):E790.
 
When appearances are misleading: About one case of primary central nervous system lymphoma (PCNSL).
Harlay V, Boissonneau S, Chinot O.
Rev Neurol (Paris). 2019 Sep - Oct;175(7-8):484-486.
 
Ophthalmoplegic complications in transsphenoidal pituitary surgery.
Florea SM, Graillon T, Cuny T, Gras R, Brue T, Dufour H.
J Neurosurg. 2019 Jul 26:1-9.
 
Clinical management of difficult to treat macroprolactinomas.
Sahakian N, Castinetti F, Dufour H, Graillon T, Romanet P, Barlier A, Brue T, Cuny T.
Expert Rev Endocrinol Metab. 2019 May;14(3):179-192.
 
Neuro-radiological characteristics of adult diffuse grade II and III insular gliomas classified according to WHO 2016.
Compes P, Tabouret E, Etcheverry A, Colin C, Appay R, Cordier N, Mosser J, Chinot O, Delingette H, Girard N, Dufour H, Metellus P, Figarella-Branger D.
J Neurooncol. 2019 May;142(3):511-520.
 
Functioning gonadotroph adenoma with severe ovarian hyperstimulation syndrome: A new emergency in pituitary adenoma surgery? Surgical considerations and literature review.
Graillon T, Castinetti F, Chabert-Orsini V, Morange I, Cuny T, Albarel F, Brue T, Dufour H.
Ann Endocrinol (Paris). 2019 Apr;80(2):122-127
 
Minimally invasive treatment of thoracolumbar flexion-distraction fracture.
Laghmouche N, Prost S, Farah K, Graillon T, Blondel B, Fuentes S.
Orthop Traumatol Surg Res. 2019 Apr;105(2):347-350.
 
Use of Cement-Augmented Percutaneous Pedicular Screws in the Management of Multifocal Tumoral Spinal Fractures.
Afathi M, Mansouri N, Farah K, Benichoux V, Blondel B, Fuentes S.
Asian Spine J. 2019 Apr;13(2):305-312.
 
Cervical osteomyelitis: A new identity of dreaded complication following pharyngeal cancer treatment.
Zamparini E, Seng P, Bardou M, Fakhry N, Graillon T, Fuentes S, Dessi P, Stein A.
Int J Infect Dis. 2019 Mar;80:118-121.
 
Treatment of aggressive recurrent meningiomas: spinning towards peptide receptor radionuclide therapy.
Guedj E, Graillon T, Chinot O, Taieb D.
Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):537-538.
 
Leptomeningeal Gliomatosis: A Single Institution Study of 31 Patients.
Autran D, Barrie M, Matta M, Monserrat C, Campello C, Petrirena G, Boucard C, Padovani L, Loundou A, Appay R, Graillon T, Dufour H, Figarella-Branger D, Chinot O, Tabouret E.
Anticancer Res. 2019 Feb;39(2):1035-1041.